As part of its $100 million renovation, Midtown Manhattan's Loews Regency Hotel called upon banner-name designers to create their own Signature Suites. On the docket: Nate Berkus, Meyer Davis Studio, Rottet Studio and Haynes-Roberts, Inc.

“We wanted to offer guests several distinct experiences,” said Jonathan Tisch, chairman of Loews Hotels and Resorts. “Each suite embodies a unique perspective and aesthetic, but together they represent a collective New York feel that Loews Regency has always evoked.”

The Signature Suites are spearheaded by Berkus' design for a suite on the 21st floor. Berkus looked to Loews Regency’s rich history and the energy of Park Avenue to create a suite that feels like home with a distinctly New York sense of style.

The 1,000-sf suite includes a formal living room, dining room, kitchen, bedroom and balcony, all fashioned in a classic mix of sand-blasted oak flooring, patinated metals and layered furnishings. Families or guests looking to entertain also have the option to book a connecting bedroom for an additional 400-sf of space.

“The challenge in designing any hotel suite is for it to not feel generic or staid,” Berkus said. “The goal is always to create a space that feels fresh and new and unexpected, like you’re stepping into someone’s home, where every detail—from the art, to the accessories on the hall table—is thought-out and deliberate.”

Meyer Davis Studio Inc., helmed by Will Meyer and Gray Davis, brought the eclectic aesthetic of SoHo and the clean lines of Chelsea to Park Avenue with the "Uptown Bohemian" suite, located on the 21st floor.

Reflecting Midtown Manhattan’s rich contemporary art scene, a light airy backdrop suggests the SoHo lofts of artists like Donald Judd, while tinted plaster walls and bold furnishings are reminiscent of contemporary artist/filmmaker Julian Schnabel. Using the artist as a muse, Meyer Davis has built the room around an eclectic, curated selection of artwork, from photography to paintings to found artifacts.

Meyer Davis Studio Inc. also designed the suite called Bespoke, located on the 20th floor, which took inspiration from the fashion industry. With a nod to designers like Halston and Geoffrey Beene, the luxury of this space is in its details: careful stitching, tailored finishing and stylish furnishings.

International architecture and design firm Rottet Studio was charged with creating The Grand Suites, a nod to Marilyn Monroe. Suite 1620, The Glamour Suite, is an interpretation of what might have been Marilyn’s Park Avenue pied-à-terre, where she lived in the 1950s. Influenced by the flowing lines and soft, indirectly lit planes of Streamline Moderne, the living room features a continuous cove light ceiling and a Wenge-clad wall (behind the 55-inch TV) that flows down into a waterfall-edge entertainment cabinet below.

The custom carpets are an updated take on the neat, tailored lines of tufted upholstery and the leopard print couture of the era. In the bedroom, a pink leather, diamond-studded headboard softly glows at the edges.

Next door is the Pop Art Suite, which plays off Marilyn’s immortalization by pop artist icon Andy Warhol. Here a “Pop Art” carpet reaches from the living room into the bedroom, where a pastel-lacquered, suede-lined wardrobe wall creates a niche for the bed's headboard. Black and white architectural finishes, inspired by comic books and ad-based Pop Art graphics, provide a bold background, while pastels, saturated primaries and jewel tones provide punchy color.

Haynes-Roberts, Inc. created the last suite to evoke the glamorous apartments of Milan in the 1970s. Richly upholstered vintage furniture and new pieces are set against a backdrop of textural building materials. In the bedrooms, velvet headboards set against suede walls are styled with over-scale vintage ceramic lamps. The selection of art and accessories is meant to suggest that the environment has been thoughtfully assembled over time.